BIOL 385 - Molecular Mechanics of Life

Credits: 4 Prerequisite: BIOL 220. How do we study complex networks of interactions between molecules in cells? How do we discover what roles different molecular machines play in the development and behavior of cells and animals? How can we identify the ways in which medical illness is caused by the misregulation of biological complexes because of a pathogenic infection or genetic disease? Our approach to answering these questions reflects the same interdisciplinary strategy being used at the forefront of current biomedical research. We consider the ways in which traditional approaches in biochemistry, genetics and cell biology can be merged with new systems-level approaches such as genomics and proteomics, to allow us to probe the underlying molecular mechanics of life. In the classroom, we examine different molecular networks, while readings include selections from the primary literature. The laboratory is based on an investigation of a novel research question, designed and addressed by student participants. Laboratory course Whitworth.