CHEM 399 - Advanced Topics in Chemistry and Biochemistry

Credits: (3 credits in fall or winter, 4 in spring)

Prerequisite: CHEM 242 or instructor consent. Studies of advanced topics. May be repeated for degree credit if the topics are different.

Spring 2016, CHEM 399-01: Advanced Topics in Chemistry and Biochemistry: Medicinal Chemistry of Blood Pressure Regulation (4). Prerequisite: CHEM 242 or instructor consent. Medicinal chemistry topics include: forces in biological systems, drug-macromolecular interactions, enzymes as drug targets, receptors as drug targets, drug action at neurotransmitter junctions, drug design, drug development and structure activity relationships, pharmacodynamics, biotransformation reactions, and drug design for pharmacokinetic problems. Student work focuses on one of the six classes of blood pressure regulators: diuretics, β-adrenergic receptor blockers, angiotensin converting enzyme inhibitors, angiotensin II receptor blockers, calcium channel blockers, and α1-adrenergic receptor agonists. Alty.